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腹腔镜治疗大于5cm胃肠间质瘤的临床疗效与安全性分析.doc

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腹腔镜治疗大于5cm胃肠间质瘤的临床疗效与安全性分析.doc
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腹腔镜治疗大于 5cm胃肠间质瘤的临床 疗效与安全性分析 王荣 徐勇 中铁一局集团中心医院普外科 西安高新医院普外科 摘 要: 目的 探讨腹腔镜治疗肿瘤>5 cm的胃肠间质瘤的临床疗效。方法 回顾性分析 2010年 1月至2012 年1月40例胃肠间质瘤患者的临床资料, 根据术式不同分 为腹腔镜组和开腹手术组, 各20例。 利用SPSS19.0 统计学软件进行分析, 两组 患者术中术后各项指标用 (x珋±s) 表示, 应用独立样本t检验;并发症发生率 采用χ2 检验;5年生存率根据 Kaplan-meier 法计算并绘制生存曲线, P0.05) 。结论 腹腔镜治疗肿瘤>5 cm 的胃肠间质瘤在手术时间上略长 于开腹手术, 但是术中出血量及术后引流量较少, 术后恢复快, 值得临床推广。 关键词: 胃肠道间质肿瘤; 腹腔镜检查; 存活率分析; 作者简介:王荣, Email:cangzhouyangbo@163.com Clinical efficacy and safety of laparoscopic surgery in treating gastrointestinal stromal tumors larger than 5cm Wang Rong Xu Yong Department of general surgery, the Central Hospital of China Railway First Bureau Group; Department of general surgery, the hi-tech hospital of city; Abstract: Objective To evaluate the clinical efficacy and safety of laparoscopic surgery in treating gastrointestinal stromal tumors larger than 5 cm. Methods Clinical data of 40 cases patients with gastrointestinal stromal tumors were analyzed retrospectively, who received laparoscopic surgery during 2010. 01 to2012. 01. All patients were randomly divided into laparoscopic group (20 cases) and open laparotomy group (20 cases) . Statistical analysis were performed by using SPSS 19. 0 software. Measurement data, such as perioperative indicators were expressed as (x 珋± s) and were examined by t test. Count data such as postoperative complications rate were examined by chi square test, Kaplan-meier was used to calculate and draw the survival curve within 5 years. A P value of 0. 05) . Conclusions The operation time of laparoscope might be longer than that of laparotomy, but the intra-operative blood loss and postoperative drainage amount would be less. with quicker recovery, which is worth of clinical promotion. Keyword: Gastrointestinal Stromal Tumors; Laparoscopy; Survival Analysis; 胃肠间质瘤 (Gastrointestinal stromal tumors, GIST) 是一种来源于原始间 叶细胞, 具有潜在恶性倾向的侵袭性肿瘤。目前认为 GIST中50%~70%是胃部间 质瘤, 十二指肠间质瘤较少见, 约占间质瘤的 4.5%, 其他见于小肠间质瘤等 [1]。GIST 对放化疗治疗均不敏感,
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