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免疫学英文考点汇总.doc

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免疫学英文考点汇总.doc
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IMMUNOLOGY GLOSSARY1、Innate immune response: the host defense mechanisms that act from the start of an infection and do not adapt to a particular antigen.2、Aadaptive immune response: the response of antigen-specific B and T lymphocytes to antigen,including the development of immunological memory.3、Accessory effector cells: In adaptive immunity, those cell aid in the response but do not directly mediate specific antigen recognition. They include phagocytes, mast cells and NK cells.4、Allergy :is a state of hypersensitivity to a normally innocuous environmental antigen. It results from the interaction between the antigen and antibodies or T cell produced by earlier exposure to the same antigen.5、Antibody:Antibody is soluble glycoprotein produced by plasma cells in response to antigen which binds with the corresponding antigen specifically.6、Anergy:It is a immune state of non-responsiveness to antigen When T and B cell are in this state, they can not respond to their specific antigen under. Usually due to lack of the second stimulator during cell activation.7、Antigen-dependent cellular cytotoxicity (ADCC):A cytotoxic reaction in which an antibody-coated target cell is directly killed by an Fc receptor-bearing leukocytes.8、Antigen: Any molecule capable of being recognized by an antibody or T-cell receptor. This group of molecules can stimulate immune response and react with the products of it.9、Apoptosis:A form of cell death in which the cell activates an internal death program. It is characterized by nuclear DNA degradation and condensation.10、Hapten: A low molecular weight molecule that is recognized by preformed antibody but is not itself immunogenic unless conjugated to a ‘carrier’molecule which provides T cell-antigen determinants.11、Superantigen:An antigen that stimulate a subset of T-cells by binding to MHC class II molecules and Vβ domains of T cell receptors, stimulating the activation of T-cell expressing particular Vβ gene segments. Therefore it stimulates a
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