碰撞池ICP_MS直接测定全血中痕量金属元素的研究_彭荣飞.pdf

[Á[ “] Ü gDÐ Sù [5(2005-YB-119, 2005-YB-115);ê 8DÐ Sù [5(A2006559)[T€eº] ® ´f(1976-), 3, « V,ö5/ =,ö1V YÏ3 ØÄ_ýT。【ÄЩçZE】碰撞池 ICP-MS直接测定全血中痕量金属元素的研究彭荣飞, 林国帧, 甘平胜, 黄聪＊(Ü g%hç] eÅϏ,Ü 510080)[K1] “¥:y ë ·ýICP-MS°¤©ç †ÓÏ’ µýí Í¥ ’sZE。ZE:¨0.1%TritonX-100+0.1%HNO3+200μg/LAu †Ó d20ª°¤¨ICP-MSÉ›s,i¨ ·/Q‹ý/ Œ Ÿh“É öÄ 。²T:œñZE¥_K¹0.04～0.98μg/L,Ú áª¿3.2%,í l q¹95.0%～ 103%。2ñS• IþÉ¥s²T 7 ¦ ¡i。² ‚: V¨ICP-MS°¤©ç †ÓAÏ¥’ µýí Í,œñZE µe†、 y ΄ ’¥+Ä。[1oM] ICP-MS;直接测定;全血;痕量有毒元素[Ïms Ë|] O657.63 [ÓDS M ’] A [ÓcI|] 1004-8685(2007)08-1433-03DirectdeterminationoftracepoisonouselementsinbloodbyinductivelycoupledplasmamassspectrometryPengRong-fei, LinGuo-zheng, GangPin-sheng, HuangCong＊(GuangzhouCenterforDiseaseControlandPrevention, Guangzhou510080,China)[Abstract] Objective:Todevelopaaccuratemethodfordirectdeterminationoftracepoisonouselementsinwholebloodbycol-lisioncellinductivelycoupledplasmamassspectrometry.Methods:Afterdilutionwith0.1%TritonX-100+0.1%HNO3 +200μg/LAubyafactorof20,thewholebloodwasdirectlydeterminedbyinductivelycoupledplasmamassspectrometrywhichusecollision/reactionceltoeliminatemassspectroscopicinterference.Results:Thedetectionlimitwas0.04～0.98μg/L, theRSDlessthan3.2%, recoveries95.0%～ 103%andtheresultsofanalyzingstandardmaterielweresatisfactory.Conclusion:Thismethodissimple,sensitiveandaccurate,andcandirectlydeterminatetracepoisonouselementsinwholeblood.[Keywords] Inductivelycoupledplasmamassspectrometry;Directdetermination;Wholeblood;Tracepoisonouselementsl? Ï 3 Yq„¯Ï 3_©Ï,ȳs †ÓÏ¥’ µýÁ ‹Be、Al、Co、Mo、Pb、Cd、V、Cr、Mn、Ni、As、Sb、Hg„Tl。ö1¨¥sZE ^ÄÐE、s;;E、ð0;E„ð0 lE,ƒtZE¥ ŒÄ ^:1)º ?Bñí ÍBñí Í¥s, Î þ ¤;2)ZE¥Ä  v,ÜÈ 4[¤ž ’²T;3) ÀµBÕZE Vs îµ¥µýí Í。7ÈËÒ†© Ö08É ö(eëICP-MS)E[  y